It was back in 1985 when Guido and Mario, good buddies, decided to take their first trip together. Thirty years later, the memories of that period overlap with their present life, for both marked by a long struggle against cancer. Nonetheless they decide to embark on a new adventure, a journey at once intimate and off the rails, rife with questions and considerations about their friendship, the meaning of life and sickness. From the windows of the conveyances which the twosome uses to hurtle through this sweet 'road movie,' the images of a changed Italy file by: the unexpected beach of their childhood at Sabaudia; the Perugia of an impromptu concert out on the streets during the Umbria Jazz Festival; the