Mistaking Spell stars Rosemary (Wadelene Joseph-Nicola), a young detective working with the Miami Police Department. Rosemary has a knack for solving crimes involving female victims. The detective has a nosy boss who gives her a special assignment involving digging into her past. Gous (Bradley Webb), a 22 year old nerd who can't find a girlfriend, decides to use a spell. A psychic gives him potions that he misuses and mistakenly switches the bottles.